February 2021 Simoa® Publications:

Other Research Areas: Oncology, Inflammation, Infectious Disease, RPPA Technology, and more

A phase 1b trial of the CXCR4 inhibitor mavorixafor and nivolumab in advanced renal cell carcinoma patients with no prior response to nivolumab monotherapy

Choueiri, T. K, et al.
Invest New Drugs (2021)

Oncology

Link to Article

Distinct profile of CD34(+) cells and plasma-derived extracellular vesicles from triple-negative patients with Myelofibrosis reveals potential markers of aggressive disease

Forte D, et al.
J Exp Clin Cancer Res 40, 49 (2021).

Oncology

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JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study

Voyer, TL, et al.
Rheumatology, keab116

Inflammation

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Dietary saturated fatty acid palmitate promotes cartilage lesions and activates the unfolded protein response pathway in mouse knee joints

Tan, L, et al.
PLoS One. 2021;16:e0247237

Inflammation

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Upregulation of IL-15 in the placenta alters trophoblasts behavior contributing to gestational diabetes mellitus

Li, J, et al.
Cell Biosci. 2021;11:33

Inflammation

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Ubiquitin Ligase SMURF2 Interacts with Filovirus VP40 and Promotes Egress of VP40 VLPs

Shepley-McTaggart, A, et al.
Viruses. 2021;13:288

Infectious Disease

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Plasma Exchange to Rescue Patients with Autoantibodies Against Type I Interferons and Life-Threatening COVID-19 Pneumonia

de Prost, N, et al.
J Clin Immunol. 2021:1-9

Infectious Disease

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Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration

Coarfa, C, et al.
J Biomol Tech. 2021 Jan 15;jbt.2021-3202-001

RPPA Technology

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Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules

Mercier, AE, et al.
Molecules 2021, 26(3), 706

Link to Article